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nmoR nmoR PA0739 PA0739 PA2076 PA2076 nmoA nmoA PA2838 PA2838 PA1225 PA1225 PA1788 PA1788 PA0234 PA0234 bexR bexR ppgL ppgL PA0191 PA0191
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
nmoRProbable transcriptional regulator; Represses its own transcription and the expression of nmoA, a nitronate monooxygenase. The nmoA-nmoR intergenic region is the sole direct binding site of NmoR across the P.aeruginosa PAO1 genome. Other genes seem also to be under negative control of NmoR, especially PA1225 and the hemO gene; Belongs to the LysR transcriptional regulatory family. (284 aa)    
Predicted Functional Partners:
PA0739
Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the LysR transcriptional regulatory family.
  
  
 0.942
PA2076
Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the LysR transcriptional regulatory family.
  
   
 0.918
nmoA
Hypothetical protein; Nitronate monooxygenase that uses molecular oxygen to catalyze the oxidative denitrification of alkyl nitronates. The toxin propionate 3-nitronate (P3N) is the best substrate (and the presumed physiological substrate), but this enzyme is also active on other primary and secondary nitronates such as propyl-1-nitronate, ethylnitronate, pentyl-1-nitronate, butyl-1-nitronate and propyl-2- nitronate. Is likely involved in the degradation of P3N, that allows P.aeruginosa PAO1 to grow on 3-nitropropionate/P3N as the sole nitrogen source. Also functions in the detoxificat [...]
  
  
 0.883
PA2838
Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the LysR transcriptional regulatory family.
  
   
 0.869
PA1225
Probable NAD(P)H dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
   
  
 0.830
PA1788
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
   
  
 0.824
PA0234
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
      
 0.822
bexR
Bistable expression regulator, BexR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa; Belongs to the LysR transcriptional regulatory family.
  
  
 0.810
ppgL
Periplasmic gluconolactonase, PpgL; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
  
  
 0.809
PA0191
Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the LysR transcriptional regulatory family.
  
   
 0.793
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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